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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Phospholipid scramblase 4

UniprotKB/SwissProt ID: Q9NRQ2 (Q9NRQ2)

Gene Name: PLSCR4

Organism: Homo sapiens (Human)

Function: Catalyzes metal ion-induced ATP-independent rapid bidirectional and non-specific movement of phospholipids (lipid scrambling or lipid flip-flop) between the inner and outer leaflet of the plasma membrane and participates in the redistribution of phospholipids between membrane leaflets (PubMed:23089641). Metal ions bind to the calcium-binding site and induce conformation change in the protein (PubMed:23089641). Has a greater affi nity for Ca(2+) than Mg(2+) and Zn(2+) (PubMed:23089641)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cell membrane. Cell membrane. Nucleus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR005552 Scramblase