Protein Name:
COMPASS-like H3K4 histone methylase component WDR5A
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UniprotKB/SwissProt ID: Q9M2Z2 (Q9M2Z2)
Gene Name:
WDR5A
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Forms multiple COMPASS-like complexes involved in histone methylation by interacting with different histone H3 'Lys-4' methyltransferases such as ATX1, SDG14 or SDG16 (PubMed:21423667). Binds to target loci chromatin, increasing H3K4 trimethylation and causing activation of the gene (PubMed:19567704). Up-regulates FLC and MAF4 expression to delay flowering (PubMed:19567704). Present at the promoters and at the transcription start sites (TSS) regions of WRKY70 and LTP7; this occupancy is ATX1-dependent (PubMed:23284292). Involved in the transition from transcription initiation to transcription elongation (PubMed:23284292)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q9M2Z2
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
189 |
CRIWDSGTGH C VKTLIDDENP |
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