Protein Name:
2-(3-amino-3-carboxypropyl)histidine synthase subunit 2
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UniprotKB/SwissProt ID: Q9M1A5 (Q9M1A5)
Gene Name:
T16L24.180
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase. Facilitates the reduction of the catalytic iron-sulfur cluster found in the DPH1 subunit
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization:
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Graphical Visualization of S-nitrosylation Sites:
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