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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: 4-trimethylaminobutyraldehyde dehydrogenase

UniprotKB/SwissProt ID: Q9JLJ2 (Q9JLJ2)

Gene Name: Aldh9a1

Organism: Mus musculus (Mouse)

Function: Converts gamma-trimethylaminobutyraldehyde into gamma-butyrobetaine with high efficiency (in vitro). Can catalyze the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction, but with low efficiency. Catalyzes the oxidation of aldehydes arising from biogenic amines and polyamines

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytosol. Cytoplasm

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR016161 Ald_DH/histidinol_DH
IPR016163 Ald_DH_C
IPR016160 Ald_DH_CS_CYS
IPR029510 Ald_DH_CS_GLU
IPR016162 Ald_DH_N
IPR015590 Aldehyde_DH_dom

The S-nitrosylation sites of Q9JLJ2

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 267 GKSPLIIFSD C NMENAVKGAL  CCCCEEEECC C CCCCCCCEEE  5.17% 21278135
2 355 LAKEQGATVL C GGEVYVPEDP  CCCCEEEECC C CCCCCCCEEE  5.98%
3 45 ATGRVIATFA C SGEKEVNLAV  CCCCEEEECC C CCCCCCCEEE  4.73% 21278135
4 484 IEYYSQLKTV C VEMGDVESAF  CCCCEEEECC C CCCCCCCEEE  2.31%
5 74 LWSKKSGLER C QVLLEAARII  CCCCEEEECC C CCCCCCCEEE  2.1%