Protein Name:
Zinc finger and BTB domain-containing protein 18
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UniprotKB/SwissProt ID: Q9JKY3 (Q9JKY3)
Gene Name:
Zbtb18
Organism: Rattus norvegicus (Rat)
Function: Transcriptional repressor that plays a role in various developmental processes such as myogenesis and brain development. Specifically binds the consensus DNA sequence 5'-[AC]ACATCTG[GT][AC]-3' which contains the E box core, and acts by recruiting chromatin remodeling multiprotein complexes. Plays a key role in myogenesis by directly repressing the expression of ID2 and ID3, 2 inhibitors of skeletal myogenesis. Also involved in controlling cell division of progenitor cells and regulating the survival of postmitotic cortical neurons. May also play a role in the organization of chromosomes in the nucleus (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q9JKY3
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
216 |
TAAGKTVASP C SSTESLSQRS |
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| 2 |
280 |
VQVKVEKEAS C DESDVGTNDY |
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| 3 |
421 |
TCSLCGKTFS C MYTLKRHERT |
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