UniprotKB/SwissProt ID: Q9JJL3 (Q9JJL3)
Gene Name:
Slco1b2
Organism: Mus musculus (Mouse)
Function: Mediates the Na(+)-independent uptake of organic anions such as taurochlate, bromosulfophthalein and steroid conjugates (estrone 3-sulfate, 17-beta-glucuronosyl estradiol, dehydroepiandrosterone sulfate). Also transports prostaglandin E2 and L-thyroxine (T4). Shows a pH-sensitive substrate specificity which may be ascribed to the protonation state of the binding site and leads to a stimulation of substrate transport in an acidic microenvironment. Hydrogencarbonate/HCO3(-) acts as the probable counteranion that exchanges for organic anions
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane
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