Protein Name:
RILP-like protein 1
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UniprotKB/SwissProt ID: Q9JJC6 (Q9JJC6)
Gene Name:
Rilpl1
Organism: Mus musculus (Mouse)
Function: Neuroprotective protein, which acts by sequestring GAPDH in the cytosol and prevent the apoptotic function of GAPDH in the nucleus (By similarity). Competes with SIAH1 for binding GAPDH (By similarity). Does not regulate lysosomal morphology and distribution (By similarity). Plays a role in the regulation of cell shape and polarity (PubMed:23264467). Plays a role in cellular protein transport, including protein transport away from primary cilia (PubMed:23264467). Binds to RAB10 following LRRK2-mediated RAB10 phosphorylation which leads to inhibition of ciliogenesis (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm, cytosol. Cell projection, cilium. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q9JJC6
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
47 |
EFERVIDQHG C ESIARLMPKV |
CCCCCCCCHH H HHHHHHCCHH |
3.3% |
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