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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Fas-activated serine/threonine kinase

UniprotKB/SwissProt ID: Q9JIX9 (Q9JIX9)

Gene Name: Fastk

Organism: Mus musculus (Mouse)

Function: Phosphorylates the splicing regulator TIA1, thereby promoting the inclusion of FAS exon 6, which leads to an mRNA encoding a pro-apoptotic form of the receptor (By similarity). Required for the biogenesis of some mitochondrial-encoded mRNAs, specifically stabilizes ND6 (NADH dehydrogenase complex subunit 6) mRNA, and regulates its levels

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion matrix

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR013579 FAST_2
IPR050870 FAST_kinase
IPR010622 FAST_Leu-rich
IPR013584 RAP