Protein Name:
Leucine-rich glioma-inactivated protein 1
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UniprotKB/SwissProt ID: Q9JIA1 (Q9JIA1)
Gene Name:
Lgi1
Organism: Mus musculus (Mouse)
Function: Regulates voltage-gated potassium channels assembled from KCNA1, KCNA4 and KCNAB1. It slows down channel inactivation by precluding channel closure mediated by the KCNAB1 subunit. Ligand for ADAM22 that positively regulates synaptic transmission mediated by AMPA-type glutamate receptors. Plays a role in suppressing the production of MMP1/3 through the phosphatidylinositol 3-kinase/ERK pathway (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Secreted. Synapse. Cytoplasm. Cytoplasm. Golgi apparatus. Secreted. Cytoplasm. Endoplasmic reticulum
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q9JIA1
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
55 |
VCTCSKDNAL C ENARSIPRTV |
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