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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Pre-mRNA-splicing factor SYF1

UniprotKB/SwissProt ID: Q9HCS7 (Q9HCS7)

Gene Name: XAB2

Organism: Homo sapiens (Human)

Function: Involved in pre-mRNA splicing as component of the spliceosome (PubMed:11991638, PubMed:28076346, PubMed:28502770). Involved in transcription-coupled repair (TCR), transcription and pre-mRNA splicing (PubMed:10944529, PubMed:17981804)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR003107 HAT
IPR055433 HAT_Syf1-like_N
IPR056350 HAT_Syf1_central
IPR055430 HAT_Syf1_CNRKL1_C
IPR045075 Syf1-like
IPR011990 TPR-like_helical_dom_sf
IPR019734 TPR_rpt

The S-nitrosylation sites of Q9HCS7

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 587 RDLFEQALDG C PPKYAKTLYL  CCEEECCCCC C CCCCCCCCCC  5.35%
2 66 LYERALKLLP C SYKLWYRYLK  CCEEECCCCC C CCCCCCCCCC  7.57% 24105792