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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Platelet glycoprotein VI

UniprotKB/SwissProt ID: Q9HCN6 (Q9HCN6)

Gene Name: GP6

Organism: Homo sapiens (Human)

Function: Collagen receptor involved in collagen-induced platelet adhesion and activation. Plays a key role in platelet procoagulant activity and subsequent thrombin and fibrin formation. This procoagulant function may contribute to arterial and venous thrombus formation. The signaling pathway involves the FcR gamma-chain, the Src kinases (likely FYN or LYN) and SYK, the adapter protein LAT and leads to the activation of PLCG2

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cell membrane. Cell membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR050412 Ig-like_Receptors_ImmuneReg
IPR003599 Ig_sub
IPR003598 Ig_sub2