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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Protein argonaute-4

UniprotKB/SwissProt ID: Q9HCK5 (Q9HCK5)

Gene Name: AGO4

Organism: Homo sapiens (Human)

Function: Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Also required for RNA-directed transcription and replication of the human hapatitis delta virus (HDV)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, P-body

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR028604 AGO4
IPR014811 ArgoL1
IPR032472 ArgoL2
IPR032473 Argonaute_Mid_dom
IPR032474 Argonaute_N
IPR003100 PAZ_dom
IPR036085 PAZ_dom_sf
IPR003165 Piwi
IPR045246 Piwi_ago-like
IPR012337 RNaseH-like_sf
IPR036397 RNaseH_sf

The S-nitrosylation sites of Q9HCK5

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 334 QKHTYLPLEV C NIVAGQRCIK