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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial

UniprotKB/SwissProt ID: Q9HCC0 (Q9HCC0)

Gene Name: MCCC2

Organism: Homo sapiens (Human)

Function: Carboxyltransferase subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3-methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion matrix

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR034733 AcCoA_carboxyl_beta
IPR029045 ClpP/crotonase-like_dom_sf
IPR011763 COA_CT_C
IPR011762 COA_CT_N
IPR045190 MCCB/AccD1-like

The S-nitrosylation sites of Q9HCC0

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 131 TGIGRVSGVE C MIIANDATVK   
2 167 QEIAMQNRLP C IYLVDSGGAY   
3 267 AEDLGGADLH C RKSGVSDHWA