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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Guanine nucleotide-binding protein subunit beta-4

UniprotKB/SwissProt ID: Q9HAV0 (Q9HAV0)

Gene Name: GNB4

Organism: Homo sapiens (Human)

Function: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR020472 G-protein_beta_WD-40_rep
IPR001632 Gprotein_B
IPR016346 Guanine_nucleotide-bd_bsu
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR019775 WD40_repeat_CS
IPR036322 WD40_repeat_dom_sf
IPR001680 WD40_rpt

The S-nitrosylation sites of Q9HAV0

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 204 PDMRTFVSGA C DASSKLWDIR   
2 25 RNQIQDARKA C NDATLVQITS   
3 271 LLLYSHDNII C GITSVAFSKS   
4 317 VLAGHDNRVS C LGVTDDGMAV