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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Queuine tRNA-ribosyltransferase accessory subunit 2

UniprotKB/SwissProt ID: Q9H974 (Q9H974)

Gene Name: QTRT2

Organism: Homo sapiens (Human)

Function: Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Mitochondrion outer membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR028592 QTRTD1
IPR050852 Queuine_tRNA-ribosyltrfase
IPR036511 TGT-like_sf
IPR002616 tRNA_ribo_trans-like

The S-nitrosylation sites of Q9H974

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 151 FQCLSDGEVS C KEATSIKRVR   
2 174 VDRSLLFLDN C LRLQEESEVL   
3 263 GVSRPDEVLE C IERGVDLFES   
4 324 DQIKKIETTG C NQEITSFEIN