Protein Name:
Protein zwilch homolog
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UniprotKB/SwissProt ID: Q9H900 (Q9H900)
Gene Name:
ZWILCH
Organism: Homo sapiens (Human)
Function: Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex (PubMed:15824131)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Chromosome, centromere, kinetochore
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q9H900
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
354 |
SDLDFAEQLW C KMSSSVISYQ |
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| 2 |
7 |
----MWERLN C AAEDFYSRLL |
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