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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Multimerin-2

UniprotKB/SwissProt ID: Q9H8L6 (Q9H8L6)

Gene Name: MMRN2

Organism: Homo sapiens (Human)

Function: Extracellular matrix protein that plays significant roles in the vascular system and is required for the maintenance and stability of blood vessel (PubMed:28435016). Affects several essential steps in angiogenesis including endothelial cell proliferation, migration, and tube formation. Positively regulates angiogenesis by acting as a ligand for CD93 receptor (PubMed:28671670, PubMed:28912033)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Secreted, extracellular space, extracellular matrix

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR001073 C1q_dom
IPR050392 Collagen/C1q_domain
IPR011489 EMI_domain
IPR008983 Tumour_necrosis_fac-like_dom