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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Inactive tyrosine-protein kinase PEAK1

UniprotKB/SwissProt ID: Q9H792 (Q9H792)

Gene Name: PEAK1

Organism: Homo sapiens (Human)

Function: Probable catalytically inactive kinase. Scaffolding protein that regulates the cytoskeleton to control cell spreading and migration by modulating focal adhesion dynamics (PubMed:20534451, PubMed:23105102, PubMed:35687021). Acts as a scaffold for mediating EGFR signaling (PubMed:23846654)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytoskeleton. Cell junction, focal adhesion

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR011009 Kinase-like_dom_sf
IPR051511 MitoQC_Scaffold_Kinases
IPR000719 Prot_kinase_dom
IPR008266 Tyr_kinase_AS

The S-nitrosylation sites of Q9H792

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 685 PDNTTSKTTD C LQTKGFSNST