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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Epidermal growth factor receptor kinase substrate 8-like protein 2

UniprotKB/SwissProt ID: Q9H6S3 (Q9H6S3)

Gene Name: EPS8L2

Organism: Homo sapiens (Human)

Function: Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton. In the cochlea, is required for stereocilia maintenance in adult hair cells (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Cell projection, stereocilium

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR039801 EPS8-like
IPR055093 EPS8_2nd
IPR033928 EPS8_PTB
IPR035462 Eps8_SH3
IPR011993 PH-like_dom_sf
IPR013625 PTB
IPR006020 PTB/PI_dom
IPR013761 SAM/pointed_sf
IPR041418 SAM_3
IPR036028 SH3-like_dom_sf
IPR001452 SH3_domain

The S-nitrosylation sites of Q9H6S3

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 369 SGPDIARSVS C PLLSRDAVDF   
2 543 SRSGQAGYVP C NILGEARPED