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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Rab GTPase-binding effector protein 2

UniprotKB/SwissProt ID: Q9H5N1 (Q9H5N1)

Gene Name: RABEP2

Organism: Homo sapiens (Human)

Function: Plays a role in membrane trafficking and in homotypic early endosome fusion (PubMed:9524116). Participates in arteriogenesis by regulating vascular endothelial growth factor receptor 2/VEGFR2 cell surface expression and endosomal trafficking (PubMed:29425100). By interacting with SDCCAG8, localizes to centrosomes and plays a critical role in ciliogenesis (PubMed:27224062)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Early endosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, cilium basal body

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR003914 Rabaptin
IPR018514 Rabaptin_coiled-coil
IPR015390 Rabaptin_Rab5-bd_dom