Protein Name:
Protein FAM83D
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UniprotKB/SwissProt ID: Q9H4H8 (Q9H4H8)
Gene Name:
FAM83D
Organism: Homo sapiens (Human)
Function: Through the degradation of FBXW7, may act indirectly on the expression and downstream signaling of MTOR, JUN and MYC (PubMed:24344117). May play also a role in cell proliferation through activation of the ERK1/ERK2 signaling cascade (PubMed:25646692). May also be important for proper chromosome congression and alignment during mitosis through its interaction with KIF22 (PubMed:18485706)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q9H4H8
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
148 |
RGAGEGGPYG C KDALRQQLRS |
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