UniprotKB/SwissProt ID: Q9H400 (Q9H400)
Gene Name:
LIME1
Organism: Homo sapiens (Human)
Function: Involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and TCR (T-cell antigen receptor)-mediated T-cell signaling in T-cells. In absence of TCR signaling, may be involved in CD4-mediated inhibition of T-cell activation. Couples activation of these receptors and their associated kinases with distal intracellular events such as calcium mobilization or MAPK activation through the recruitment of PLCG2, GRB2, GRAP2, and other signaling molecules
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane
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