Protein Name:
Protein unc-45 homolog A
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UniprotKB/SwissProt ID: Q9H3U1 (Q9H3U1)
Gene Name:
UNC45A
Organism: Homo sapiens (Human)
Function: Acts as a co-chaperone for HSP90. Prevents the stimulation of HSP90AB1 ATPase activity by AHSA1. Positive factor in promoting PGR function in the cell. May be necessary for proper folding of myosin (Potential). Necessary for normal cell proliferation. Necessary for normal myotube formation and myosin accumulation during muscle cell development. May play a role in erythropoiesis in stroma cells in the spleen (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Cytoplasm, perinuclear region. Nucleus
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q9H3U1
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
223 |
LAALRTLVGI C SEHQSRTVAT |
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| 2 |
34 |
LRKEGNELFK C GDYGGALAAY |
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| 3 |
384 |
LLSKLFDDLK C DAERENFHRL |
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| 4 |
395 |
DAERENFHRL C ENYIKSWFEG |
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| 5 |
420 |
GKLRAIQTVS C LLQGPCDAGN |
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| 6 |
535 |
KLAKQCRKWL C NDQIDAGTRR |
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| 7 |
663 |
KTESPVLTSS C RELLSRVFLA |
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