Protein Name:
Negative elongation factor A
|
UniprotKB/SwissProt ID: Q9H3P2 (Q9H3P2)
Gene Name:
NELFA
Organism: Homo sapiens (Human)
Function: Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex (Microbial infection) The NELF complex is involved in HIV-1 latency possibly involving recruitment of PCF11 to paused RNA polymerase II
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus
|
|
|
Graphical Visualization of S-nitrosylation Sites:
|
|
The S-nitrosylation sites of Q9H3P2
|
| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
131 |
LGELREKVGE C EASAMLPLEC |
|
|
|
| 2 |
141 |
CEASAMLPLE C QYLNKNALTT |
|
|
|
| 3 |
471 |
GFMAGSRENP C QEQGDVIQIK |
|
|
|
|
