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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Inorganic pyrophosphatase 2, mitochondrial

UniprotKB/SwissProt ID: Q9H2U2 (Q9H2U2)

Gene Name: PPA2

Organism: Homo sapiens (Human)

Function: Hydrolyzes inorganic pyrophosphate (PubMed:27523597). This activity is essential for correct regulation of mitochondrial membrane potential, and mitochondrial organization and function (PubMed:27523598)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR008162 Pyrophosphatase
IPR036649 Pyrophosphatase_sf

The S-nitrosylation sites of Q9H2U2

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 161 DPHEKDKSTN C FGDNDPIDVC  CHHHHHHHHH C CCHHHHHHHC  4.01%
2 171 CFGDNDPIDV C EIGSKILSCG  CHHHHHHHHH C CCHHHHHHHC  2.53%
3 180 VCEIGSKILS C GEVIHVKILG  CHHHHHHHHH C CCHHHHHHHC  4.89% 19483679
4 44 LYHTEERGQP C SQNYRLFFKN  CHHHHHHHHH C CCHHHHHHHC  5.13%