Protein Name:
TRIO and F-actin-binding protein
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UniprotKB/SwissProt ID: Q9H2D6 (Q9H2D6)
Gene Name:
TRIOBP
Organism: Homo sapiens (Human)
Function: Regulates actin cytoskeletal organization, cell spreading and cell contraction by directly binding and stabilizing filamentous F-actin and prevents its depolymerization (PubMed:18194665, PubMed:28438837). May also serve as a linker protein to recruit proteins required for F-actin formation and turnover (PubMed:18194665). Essential for correct mitotic progression (PubMed:22820163, PubMed:24692559) Plays a pivotal role in the formation of stereocilia rootlets Plays a pivotal role in the formation of stereocilia rootlets
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Midbody. Chromosome, telomere
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q9H2D6
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
1842 |
ELDGEIDLRS C TDVTEYAVQR |
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| 2 |
2280 |
GCGRSNERSS C ELEVLLRVKE |
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