Protein Name:
Gigaxonin
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UniprotKB/SwissProt ID: Q9H2C0 (Q9H2C0)
Gene Name:
GAN
Organism: Homo sapiens (Human)
Function: Probable cytoskeletal component that directly or indirectly plays an important role in neurofilament architecture. May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Controls degradation of TBCB. Controls degradation of MAP1B and MAP1S, and is critical for neuronal maintenance and survival
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Cytoplasm, cytoskeleton
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q9H2C0
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
464 |
LKERRFGAVA C GVAMELYVFG |
CCCCCCCCCH H HHHHHHHHHH |
3.46% |
22178444
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