Protein Name:
Oxysterol-binding protein-related protein 2
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UniprotKB/SwissProt ID: Q9H1P3 (Q9H1P3)
Gene Name:
OSBPL2
Organism: Homo sapiens (Human)
Function: Intracellular transport protein that binds sterols and phospholipids and mediates lipid transport between intracellular compartments. Increases plasma membrane cholesterol levels and decreases phosphatidylinositol-4,5-bisphosphate levels in the cell membrane (PubMed:30581148). Binds phosphoinositides, such as phosphatidylinositol-4,5-bisphosphate (PubMed:30581148). Exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3-phosphate (PubMed:11279184). Binds cholesterol, dehydroergosterol, 22(R)-hydroxycholesterol and 25-hydroxycholesterol (in vitro) (PubMed:17428193, PubMed:19224871, PubMed:30581148)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm, cytosol. Lipid droplet. Cell membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q9H1P3
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
122 |
EHVYLIHRAS C QPQPLERMQS |
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