Protein Name:
Protein unc-93 homolog B1
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UniprotKB/SwissProt ID: Q9H1C4 (Q9H1C4)
Gene Name:
UNC93B1
Organism: Homo sapiens (Human)
Function: Plays an important role in innate and adaptive immunity by regulating nucleotide-sensing Toll-like receptor (TLR) signaling. Required for the transport of a subset of TLRs (including TLR3, TLR7 and TLR9) from the endoplasmic reticulum to endolysosomes where they can engage pathogen nucleotides and activate signaling cascades. May play a role in autoreactive B-cells removal
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Endoplasmic reticulum membrane. Endosome. Lysosome. Cytoplasmic vesicle, phagosome
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q9H1C4
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
583 |
PEPAGLGRRP C PYEQAQGGDG |
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