UniprotKB/SwissProt ID: Q9H0W8 (Q9H0W8)
Gene Name:
SMG9
Organism: Homo sapiens (Human)
Function: Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons (PubMed:19417104). Is recruited by release factors to stalled ribosomes together with SMG1 and SMG8 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required for the efficient association between SMG1 and SMG8 (PubMed:19417104). Plays a role in brain, heart, and eye development (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization:
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