Protein Name:
Integrin-linked kinase-associated serine/threonine phosphatase 2C
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UniprotKB/SwissProt ID: Q9H0C8 (Q9H0C8)
Gene Name:
ILKAP
Organism: Homo sapiens (Human)
Function: Protein phosphatase that may play a role in regulation of cell cycle progression via dephosphorylation of its substrates whose appropriate phosphorylation states might be crucial for cell proliferation. Selectively associates with integrin linked kinase (ILK), to modulate cell adhesion and growth factor signaling. Inhibits the ILK-GSK3B signaling axis and may play an important role in inhibiting oncogenic transformation
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q9H0C8
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
190 |
VISVEKTVKR C LLDTFKHTDE |
CCCCCCCCCC C CCCCCCCCCC |
3.52% |
19483679
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| 2 |
221 |
PAWKDGSTAT C VLAVDNILYI |
CCCCCCCCCC C CCCCCCCCCC |
1.88% |
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| 3 |
301 |
RSIGDGQYKR C GVTSVPDIRR |
CCCCCCCCCC C CCCCCCCCCC |
4.49% |
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| 4 |
312 |
GVTSVPDIRR C QLTPNDRFIL |
CCCCCCCCCC C CCCCCCCCCC |
2.53% |
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| 5 |
367 |
SAADARYEAA C NRLANKAVQR |
CCCCCCCCCC C CCCCCCCCCC |
3.82% |
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