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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: BTB/POZ domain-containing protein 1

UniprotKB/SwissProt ID: Q9H0C5 (Q9H0C5)

Gene Name: BTBD1

Organism: Homo sapiens (Human)

Function: Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (PubMed:14528312). Seems to regulate expression levels and/or subnuclear distribution of TOP1, via an unknown mechanism (By similarity). May play a role in mesenchymal differentiation where it promotes myogenic differentiation and suppresses adipogenesis (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR011705 BACK
IPR000210 BTB/POZ_dom
IPR012983 PHR
IPR038648 PHR_sf
IPR011333 SKP1/BTB/POZ_sf

The S-nitrosylation sites of Q9H0C5

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 400 TLGQNDTGFS C DGTANTFRVM