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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Kinesin light chain 2

UniprotKB/SwissProt ID: Q9H0B6 (Q9H0B6)

Gene Name: KLC2

Organism: Homo sapiens (Human)

Function: Kinesin is a microtubule-associated force-producing protein that plays a role in organelle transport. The light chain functions in coupling of cargo to the heavy chain or in the modulation of its ATPase activity (Probable). Through binding with PLEKHM2 and ARL8B, recruits kinesin-1 to lysosomes and hence direct lysosomes movement toward microtubule plus ends (PubMed:22172677)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytoskeleton. Lysosome membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR002151 Kinesin_light
IPR015792 Kinesin_light_repeat
IPR011990 TPR-like_helical_dom_sf
IPR019734 TPR_rpt

The S-nitrosylation sites of Q9H0B6

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 221 QGRYEVAVPL C KQALEDLEKT   
2 305 RGKYKEAEPL C KRALEIREKV   
3 375 VAKTKNNLAS C YLKQGKYQDA   
4 474 KLEAAHTLED C ASRNRKQGLD