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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: SRA stem-loop-interacting RNA-binding protein, mitochondrial

UniprotKB/SwissProt ID: Q9GZT3 (Q9GZT3)

Gene Name: SLIRP

Organism: Homo sapiens (Human)

Function: RNA-binding protein that acts as a nuclear receptor corepressor. Probably acts by binding the SRA RNA, and repressing the SRA-mediated nuclear receptor coactivation. Binds the STR7 loop of SRA RNA. Also able to repress glucocorticoid (GR), androgen (AR), thyroid (TR) and VDR-mediated transactivation

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion. Nucleus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR000504 RRM_dom
IPR052462 SLIRP/GR-RBP-like
IPR034152 SLIRP_RRM

The S-nitrosylation sites of Q9GZT3

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 48 HFAQFGHVRR C ILPFDKETGF  CHHHHHHHHH H HHHHCCCCEE  2.34% 19483679
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