Protein Name:
DNA-directed RNA polymerase I subunit RPA49
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UniprotKB/SwissProt ID: Q9GZS1 (Q9GZS1)
Gene Name:
POLR1E
Organism: Homo sapiens (Human)
Function: Component of RNA polymerase I (Pol I), a DNA-dependent RNA polymerase which synthesizes ribosomal RNA precursors using the four ribonucleoside triphosphates as substrates (PubMed:24207024, PubMed:34671025, PubMed:34887565, PubMed:36271492). Appears to be involved in the formation of the initiation complex at the promoter by mediating the interaction between Pol I and UBTF/UBF (PubMed:24207024)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus, nucleolus
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Graphical Visualization of S-nitrosylation Sites:
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| InterPro ID |
Domain Name |
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IPR009668
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RNA_pol-assoc_fac_A49-like |
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The S-nitrosylation sites of Q9GZS1
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
138 |
TKTYREKMDS C IEAFGTTKQK |
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| 2 |
316 |
INTKLLKHFT C LTYNNGRLRN |
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