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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: 5'-3' exoribonuclease 3

UniprotKB/SwissProt ID: Q9FQ03 (Q9FQ03)

Gene Name: XRN3

Organism: Arabidopsis thaliana (Mouse-ear cress)

Function: Possesses 5'->3' exoribonuclease activity (PubMed:11106401). Acts as an endogenous post-transcriptional gene silencing (PTGS) suppressor. Degrades miRNA-derived loops, excised during miRNA maturation in the nucleus. Required for proper development (PubMed:17993620). Involved in pre-rRNA processing. Involved with XRN2 in the 5'-end exonucleolytic processing of 5.8S and 25S rRNAs. Contributes with XRN2 to polyadenylation-dependent nuclear RNA surveillance. Involved in the degradation of aberrant polyadenylated pre-rRNA through 5'-end processing (PubMed:20338880)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR027073 5_3_exoribonuclease
IPR041412 Xrn1_helical
IPR004859 Xrn1_N
IPR017151 Xrn2/3/4
IPR001878 Znf_CCHC
IPR036875 Znf_CCHC_sf

The S-nitrosylation sites of Q9FQ03

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 383 RSFDGYLTDG C KPNLKRVEQF