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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: ARF guanine-nucleotide exchange factor GNL1

UniprotKB/SwissProt ID: Q9FLY5 (Q9FLY5)

Gene Name: GNL1

Organism: Arabidopsis thaliana (Mouse-ear cress)

Function: Activates the ARF proteins by exchanging bound GDP for free GTP. Plays a role in vesicular protein sorting. Acts as the major regulator of retrograde Golgi to endoplasmic reticulum trafficking but is also involved in the endocytosis process. Could function redundantly with GNOM. Regulates vesicle trafficking required for the coordinated polar localization of auxin efflux carriers which in turn determines the direction of auxin flow. Mediates the endocytosis of PIN2 from plasma membrane to endosomal compartments. Required for maintenance of endoplasmic reticulum morphology

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytosol. Golgi apparatus membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR056604 GBF1-like_TPR
IPR032691 Mon2/Sec7/BIG1-like_HUS
IPR023394 Sec7_C_sf
IPR000904 Sec7_dom
IPR035999 Sec7_dom_sf