\
logo
  Home | Contact us | Browse | Quick Search by UniProtKB ID, Keyword, PDBID

Menu:

Latest news:

Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

Read more...


Protein Name: Ribonuclease TUDOR 2

UniprotKB/SwissProt ID: Q9FLT0 (Q9FLT0)

Gene Name: TSN2

Organism: Arabidopsis thaliana (Mouse-ear cress)

Function: Cytoprotective ribonuclease (RNase) required for resistance to abiotic stresses, acting as a positive regulator of mRNA decapping during stress (PubMed:25736060). Essential for the integrity and function of cytoplasmic messenger ribonucleoprotein (mRNP) complexes called stress granules (SGs) and processing bodies (PBs), sites of post-transcriptional gene regulation during stress (e.g. salt and heat) (PubMed:25736060). Involved in gibberellic acid (GA) biosynthesis and seed germination (PubMed:20396901). Essential for stress tolerance, probably by regulating mRNAs entering the secretory pathway (PubMed:20484005). Component of stress granules (SGs) that regulates growth under salt stress by modulating levels of GA20OX3 mRNA. Binds GA20OX3 mRNA (By similarity). May inhibit the degradation of mRNAs involved in stress adaptation (PubMed:26237081)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Cytoplasm, perinuclear region. Endoplasmic reticulum. Cytoplasmic granule

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR016685 Silence_cplx_Nase-comp_TudorSN
IPR035437 SNase_OB-fold_sf
IPR016071 Staphylococal_nuclease_OB-fold
IPR002999 Tudor
IPR047395 Tudor_AtTudor1-like

The S-nitrosylation sites of Q9FLT0

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 24 GRVKAVTSGD C LVITALTHNR   
2 358 KKKLKATELQ C KKNRVKMWAN   
3 396 GKVVEVVSGD C LVVADDSIPF   
4 606 RFKLYIPKES C SIAFAFSGVR   
5 850 VSSAPGLAQL C RLAYIKVPGK