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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: 2-oxoglutarate dehydrogenase, mitochondrial

UniprotKB/SwissProt ID: Q9FLH2 (Q9FLH2)

Gene Name: MPA24.10

Organism: Arabidopsis thaliana (Mouse-ear cress)

Function: The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion matrix

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR032106 2-oxogl_dehyd_N
IPR011603 2oxoglutarate_DH_E1
IPR001017 DH_E1
IPR042179 KGD_C_sf
IPR031717 ODO-1/KGD_C
IPR029061 THDP-binding
IPR005475 Transketolase-like_Pyr-bd

The S-nitrosylation sites of Q9FLH2

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 453 DPREGRSSQY C TDVAKALSAP   
2 688 LHDQETGEEY C PLDHLIKNQD   
3 855 APKNLLRHKQ C VSNLSEFDDV