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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: LRR receptor-like serine/threonine-protein kinase FLS2

UniprotKB/SwissProt ID: Q9FL28 (Q9FL28)

Gene Name: FLS2

Organism: Arabidopsis thaliana (Mouse-ear cress)

Function: Constitutes the pattern-recognition receptor (PPR) that determines the specific perception of flagellin (flg22), a potent elicitor of the defense response to pathogen-associated molecular patterns (PAMPs). Flagellin-binding to the receptor is the first step to initiate the innate immune MAP kinase signaling cascade (MEKK1, MKK4/MKK5 and MPK3/MPK6), resulting in enhanced resistance against pathogens. Binding to the effector AvrPto1 or to the phosphatase hopD2 from Pseudomonas syringae blocks the downstream plant immune response

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cell membrane. Endosome membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR011009 Kinase-like_dom_sf
IPR001611 Leu-rich_rpt
IPR003591 Leu-rich_rpt_typical-subtyp
IPR032675 LRR_dom_sf
IPR013210 LRR_N_plant-typ
IPR055414 LRR_R13L4/SHOC2-like
IPR050647 Plant_LRR-RLKs
IPR000719 Prot_kinase_dom
IPR008271 Ser/Thr_kinase_AS