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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Cytochrome P450 3A

UniprotKB/SwissProt ID: Q9EQW4 (Q9EQW4)

Gene Name: Cyp3a44

Organism: Mus musculus (Mouse)

Function: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Endoplasmic reticulum membrane. Microsome membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR001128 Cyt_P450
IPR017972 Cyt_P450_CS
IPR008072 Cyt_P450_E_CYP3A
IPR002402 Cyt_P450_E_grp-II
IPR036396 Cyt_P450_sf
IPR050705 Cytochrome_P450_3A

The S-nitrosylation sites of Q9EQW4

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 469 KVLQNFSFQP C QETQIPLKLS