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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Dihydropyrimidinase

UniprotKB/SwissProt ID: Q9EQF5 (Q9EQF5)

Gene Name: Dpys

Organism: Mus musculus (Mouse)

Function: Catalyzes the second step of the reductive pyrimidine degradation, the reversible hydrolytic ring opening of dihydropyrimidines. Can catalyze the ring opening of 5,6-dihydrouracil to N-carbamyl-alanine and of 5,6-dihydrothymine to N-carbamyl-amino isobutyrate (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR006680 Amidohydro-rel
IPR011778 Hydantoinase/dihydroPyrase
IPR011059 Metal-dep_hydrolase_composite
IPR032466 Metal_Hydrolase
IPR050378 Metallo-dep_Hydrolases_sf

The S-nitrosylation sites of Q9EQF5

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 220 GITGPEGHEL C RPEAVEAEAT  CCCCCCEEEE C CEECCCCHHH  6.59% 22178444
2 242 RAITIASAVN C PLYVVHVMSK  CCCCCCEEEE C CEECCCCHHH  1.65% 22178444
3 433 VNFNIFEGMV C HGVPLVTISR  CCCCCCEEEE C CEECCCCHHH  1.39%
4 483 YKRIKQRDQT C TPVPVKRAPY  CCCCCCEEEE C CEECCCCHHH  3.17% 22178444