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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial

UniprotKB/SwissProt ID: Q9EQ20 (Q9EQ20)

Gene Name: Aldh6a1

Organism: Mus musculus (Mouse)

Function: Malonate and methylmalonate semialdehyde dehydrogenase involved in the catabolism of valine, thymine, and compounds catabolized by way of beta-alanine, including uracil and cytidine

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR016161 Ald_DH/histidinol_DH
IPR016163 Ald_DH_C
IPR016160 Ald_DH_CS_CYS
IPR016162 Ald_DH_N
IPR015590 Aldehyde_DH_dom
IPR010061 MeMal-semiAld_DH

The S-nitrosylation sites of Q9EQ20

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 149 FRGLQVVEHA C SVTSLMLGET  CHHHHHHHHH H HHHHCHHHCC  3.47% 21278135
2 249 HGQHDAVNFI C DHPDIKAISF  CHHHHHHHHH H HHHHCHHHCC  3.26%
3 317 GAAFGAAGQR C MALSTAILVG  CHHHHHHHHH H HHHHCHHHCC  1.12%
4 368 LITPQAKERV C NLIDSGTKEG  CHHHHHHHHH H HHHHCHHHCC  4.25% 21278135
5 413 IISNVKPSMT C YKEEIFGPVL  CHHHHHHHHH H HHHHCHHHCC  3.23% 21278135
6 86 KAEMDAAVES C KRAFPAWADT  CHHHHHHHHH H HHHHCHHHCC  1.88% 21278135