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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Electron transfer flavoprotein subunit beta

UniprotKB/SwissProt ID: Q9DCW4 (Q9DCW4)

Gene Name: Etfb

Organism: Mus musculus (Mouse)

Function: Heterodimeric electron transfer flavoprotein that accepts electrons from several mitochondrial dehydrogenases, including acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (By similarity). Required for normal mitochondrial fatty acid oxidation and normal amino acid metabolism (PubMed:25023281). ETFB binds an AMP molecule that probably has a purely structural role (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion matrix

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR000049 ET-Flavoprotein_bsu_CS
IPR014730 ETF_a/b_N
IPR012255 ETF_b
IPR033948 ETF_beta_N
IPR014729 Rossmann-like_a/b/a_fold

The S-nitrosylation sites of Q9DCW4

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 131 FLGKQAIDDD C NQTGQMTAGL  CHHHHHHHHH H HHHEEEEEEE  5.38% 21278135
2 42 DGVKHSMNPF C EIAVEEAVRL  CHHHHHHHHH H HHHEEEEEEE  3.79% 22178444
21278135
3 66 KLVKEIIAVS C GPSQCQETIR  CHHHHHHHHH H HHHEEEEEEE  8.15%
4 71 IIAVSCGPSQ C QETIRTALAM  CHHHHHHHHH H HHHEEEEEEE  4.66%