Protein Name:
Glycine amidinotransferase, mitochondrial
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UniprotKB/SwissProt ID: Q9D964 (Q9D964)
Gene Name:
Gatm
Organism: Mus musculus (Mouse)
Function: Transamidinase that catalyzes the transfer of the amidino group of L-arginine onto the amino moiety of acceptor metabolites such as glycine, beta-alanine, gamma-aminobutyric acid (GABA) and taurine yielding the corresponding guanidine derivatives (By similarity). Catalyzes the rate-limiting step of creatine biosynthesis, namely the transfer of the amidino group from L-arginine to glycine to generate guanidinoacetate, which is then methylated by GAMT to form creatine. Provides creatine as a source for ATP generation in tissues with high energy demands, in particular skeletal muscle, heart and brain (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Mitochondrion inner membrane
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Graphical Visualization of S-nitrosylation Sites:
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| InterPro ID |
Domain Name |
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IPR033195
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AmidinoTrfase |
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The S-nitrosylation sites of Q9D964
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
407 |
NANSLGGGFH C WTCDVRRRGT |
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| 2 |
50 |
QAATASSRNS C AAEDKATHPL |
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| 3 |
64 |
DKATHPLPKD C PVSSYNEWDP |
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