Protein Name:
Marginal zone B- and B1-cell-specific protein
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UniprotKB/SwissProt ID: Q9D8I1 (Q9D8I1)
Gene Name:
Mzb1
Organism: Mus musculus (Mouse)
Function: Associates with immunoglobulin M (IgM) heavy and light chains and promotes IgM assembly and secretion. May exert its effect by acting as a molecular chaperone or as an oxidoreductase as it displays a low level of oxidoreductase activity. Helps to diversify peripheral B-cell functions by regulating Ca(2+) stores, antibody secretion and integrin activation Acts as a hormone-regulated adipokine/pro-inflammatory cytokine that is implicated in causing chronic inflammation, affecting cellular expansion and blunting insulin response in adipocytes. May have a role in the onset of insulin resistance
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Endoplasmic reticulum. Endoplasmic reticulum lumen. Secreted
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Graphical Visualization of S-nitrosylation Sites:
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