Protein Name:
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma
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UniprotKB/SwissProt ID: Q9D517 (Q9D517)
Gene Name:
Agpat3
Organism: Mus musculus (Mouse)
Function: Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone (PubMed:15367102). Acts on LPA containing saturated or unsaturated fatty acids C16:0-C20:4 at the sn-1 position using C18:1, C20:4 or C18:2-CoA as the acyl donor (By similarity). Also acts on lysophosphatidylcholine, lysophosphatidylinositol and lysophosphatidylserine using C18:1 or C20:4-CoA (By similarity). Has a preference for arachidonoyl-CoA as a donor (PubMed:19114731). Also has a modest lysophosphatidylinositol acyltransferase (LPIAT) activity, converts lysophosphatidylinositol (LPI) into phosphatidylinositol (PubMed:19114731)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Endoplasmic reticulum membrane. Nucleus envelope
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q9D517
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
217 |
RTKGFTTAVQ C LRGTVAAIYD |
CCHHHHHHHH H HHHHHHHHHH |
1.94% |
21278135
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| 2 |
254 |
LYGKKYEADM C VRRFPLEDIP |
CCHHHHHHHH H HHHHHHHHHH |
1.9% |
21278135
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