Protein Name:
Epoxide hydrolase 1
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UniprotKB/SwissProt ID: Q9D379 (Q9D379)
Gene Name:
Ephx1
Organism: Mus musculus (Mouse)
Function: Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. May play a role in the metabolism of endogenous lipids such as epoxide-containing fatty acids. Metabolizes the abundant endocannabinoid 2-arachidonoylglycerol (2-AG) to free arachidonic acid (AA) and glycerol (By similarity). Binds 20(S)-hydroxycholesterol (20(S)-OHC) (PubMed:34799735)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Microsome membrane. Endoplasmic reticulum membrane
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Graphical Visualization of S-nitrosylation Sites:
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