\
logo
  Home | Contact us | Browse | Quick Search by UniProtKB ID, Keyword, PDBID

Menu:

Latest news:

Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

Read more...


Protein Name: Endoplasmic reticulum resident protein 44

UniprotKB/SwissProt ID: Q9D1Q6 (Q9D1Q6)

Gene Name: Erp44

Organism: Mus musculus (Mouse)

Function: Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1A and ERO1B in the endoplasmic reticulum

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Endoplasmic reticulum lumen

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR052643 ERP44
IPR041862 ERp44_PDI_b
IPR041870 ERp44_PDI_b
IPR036249 Thioredoxin-like_sf
IPR013766 Thioredoxin_domain

The S-nitrosylation sites of Q9D1Q6

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 92 KNQVVFARVD C DQHSDIAQRY  CCHHHHHHHH H HHHHHHHHHH  5.05% 22178444
21278135