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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Tubulin-folding cofactor B

UniprotKB/SwissProt ID: Q9D1E6 (Q9D1E6)

Gene Name: Tbcb

Organism: Mus musculus (Mouse)

Function: Binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway leading from newly synthesized tubulin to properly folded heterodimer (By similarity). Involved in regulation of tubulin heterodimer dissociation (PubMed:17184771). May function as a negative regulator of axonal growth (PubMed:17217416)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Cytoplasm, cytoskeleton

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR036859 CAP-Gly_dom_sf
IPR000938 CAP-Gly_domain
IPR045172 TBCB_Ubl
IPR000626 Ubiquitin-like_dom
IPR029071 Ubiquitin-like_domsf

The S-nitrosylation sites of Q9D1E6

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 83 LLGSYPVDDG C RIHVIDHSGV  CCCCCCCCCE E EEEEHHHHHH  4.8% 21278135